PULMONARY HISTIOCYTOSIS X

Primary pulmonary histiocytosis X.

During the past 40 years, three previously unrecognized disorders of the reticuloendothelial system have been described : Letterer-Siwe’s disease,’ Hand-Sch#{252}ller-Christian’s disease,24 and eosinophilic granuloma.5’6 Due largely to the influence of Lichtenstein,7 the opinion now prevails that these three disorders are fundamentally related. They differ from one another mainly in terms of pa...

The clinical role of BAL in pulmonary histiocytosis X.

detection of trace metals in the cell-free BAL fluid, showing high concentrations of tungsten (W), tantalum (Ta) and cobalt (Co) in hard metal lung disease [163]. The quantification of asbestos bodies is best done by filtration of 5-15 ml fresh BAL fluid, cells included, onto millipore filters, and counting the number of asbestos bodies [179]. Uncoated asbestos fibres can only be counted by ele...

Bronchogenic carcinoma in patients with pulmonary histiocytosis X.

Five cases of bronchogenic carcinoma were observed among 93 patients with pulmonary histiocytosis X (Hx). Mean age at the time of diagnosis of Hx was 42 years; on the average, cancer occurred 10.5 years later. All patients were smokers and continued to smoke heavily at the time of diagnosis of cancer. Comparison of the five cases associating Hx and lung carcinoma with a group of 88 control pati...

Primary pulmonary histiocytosis X in two patients with Hodgkin's disease.

The lungs may be involved in patients with histiocytosis X as part of the generalised disease, but histiocytosis X confined to the lungs without extrapulmonary involvement is rare. This report describes two cases of primary pulmonary histiocytosis arising in patients with Hodgkin's disease. It is impossible to state with certainty whether the pulmonary histiocytosis arose as a response to the d...

Group II phospholipase A2 and pulmonary histiocytosis X.